Amlodipine besilate price index

Amlodipine besilate price December 2025 and outlook (see chart below)

• Global:US$28.03/KG, -0.5% down

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Amlodipine besilate price index

This post is a summary of the Amlodipine besilate price developments. The price developments of Amlodipine besilate are expressed in US$ prices converted FX rates applicable at the time when the price was valid. Amlodipine besilate price index developments are calculated from multiple separate sources of data to ensure statistical accuracy.

The outlook for Amlodipine besilate prices is generated from different inputs including:

• Very recent price developments of immediate cost drivers of Amlodipine besilate prices
• Recent price developments of underlying feedstocks which drive the price of Amlodipine besilate
• Market futures for both cost drives and feedstocks of Amlodipine besilate prices
• Adjustment of current supply/demand imbalances in the Amlodipine besilate market
• Longer term trends in likely demand conditions

What is Amlodipine besilate and what is it used for

Amlodipine besilate (also written amlodipine besylate) is the besilate (besylate) salt of amlodipine, a long-acting dihydropyridine calcium-channel blocker used primarily to treat hypertension (high blood pressure) and angina (chest pain). It relaxes and widens blood vessels, lowering blood pressure and improving blood flow to the heart; it is widely available as a generic and is included on essential-medicines lists.

How is Amlodipine besilate produced

Commercial manufacture proceeds by synthetic organic chemistry from the amlodipine base followed by conversion to the besilate salt and crystallisation to give a stable pharmaceutical API. Published processes and patents describe key steps such as formation of protected intermediates (e.g., phthalimido-amlodipine), aminolysis to the amlodipine base, and final salt formation/crystallisation to high-purity besylate. Scale-up and formulation work focus on controlling polymorph, residual solvents and moisture to meet pharmacopeial and regulatory requirements.

How large is the global market for Amlodipine besilate

Market estimates vary by source and the scope (API vs finished-dose, single-ingredient vs combinations). Recent market reports place the global amlodipine/amlodipine-besylate market in the low billions USD: examples include ~USD 1.9–2.2 billion (reported for 2023–2024 by industry research firms) and alternative reports projecting a range from ~USD 0.4–2.9 billion over different forecast horizons and definitions. Reported compound annual growth rates (CAGRs) are typically in the ~3–5% range driven by the high prevalence of hypertension and generic uptake. Because methodologies differ, treat any single figure as an estimate and consult the original market report for the precise scope and year.

Where is Amlodipine besilate produced

Amlodipine besilate is manufactured globally by many API producers and finished-dose generics manufacturers. Large API and generic producers in India and China are major suppliers of amlodipine API; there are also European and multinational pharmaceutical companies (and legacy brand owners such as Pfizer/Upjohn/Viatris historically for Norvasc) that supply finished products or licensed formulations. Supplier lists and directories show multiple manufacturers (e.g., Dr. Reddy’s, various Indian API houses and contract manufacturers), so production is geographically distributed across India, China, Europe and other contract-manufacturing centres.