Ampicillin Trihydrate price index

Ampicillin Trihydrate price December 2025 and outlook (see chart below)

• India:US$25.44/KG, -0.1% down

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Ampicillin Trihydrate price index

This post is a summary of the Ampicillin Trihydrate price developments. The price developments of Ampicillin Trihydrate are expressed in US$ prices converted FX rates applicable at the time when the price was valid. Ampicillin Trihydrate price index developments are calculated from multiple separate sources of data to ensure statistical accuracy.

The outlook for Ampicillin Trihydrate prices is generated from different inputs including:

• Very recent price developments of immediate cost drivers of Ampicillin Trihydrate prices
• Recent price developments of underlying feedstocks which drive the price of Ampicillin Trihydrate
• Market futures for both cost drives and feedstocks of Ampicillin Trihydrate prices
• Adjustment of current supply/demand imbalances in the Ampicillin Trihydrate market
• Longer term trends in likely demand conditions

What is Ampicillin Trihydrate and what is it used for

Ampicillin trihydrate is the trihydrate crystalline form of ampicillin, a broad-spectrum, β-lactam (penicillin) antibiotic used to treat or prevent infections caused by susceptible Gram-positive and some Gram-negative bacteria. It is used in human and veterinary medicine for conditions such as respiratory, urinary tract, gastrointestinal and meningitic infections, and is also widely used in laboratory applications (e.g., selection of bacterial transformants). :contentReference[oaicite:0]{index=0}

How is Ampicillin Trihydrate produced

Ampicillin is typically produced by acylation of 6-aminopenicillanic acid (6-APA) with a phenylglycine derivative (for example D-(-)-α-phenylglycine chloride or related intermediates). Production routes include classical chemical acylation and enzymatic (biocatalytic) acylation methods; after synthesis the free base is converted into the trihydrate crystalline form by controlled crystallization from aqueous solvent to yield ampicillin trihydrate. Multiple patents and technical descriptions cover both chemical and enzymatic batch processes and downstream crystallization steps.

How large is the global market for Ampicillin Trihydrate and where is it produced

Market estimates for ampicillin trihydrate vary between commercial research reports, but several industry reports place the global ampicillin/ampicillin-trihydrate market in the hundreds of millions to low billions of USD (different vendors report different base years, scopes and splitting between API vs finished formulations). Forecasts in publicly advertised market reports show moderate growth (single-digit CAGR) over the next 5–10 years driven by continued demand for established antibiotics and use in both human and veterinary sectors; because these figures are report-dependent, treating any single published number as definitive is not advisable.

Production of ampicillin/ampicillin trihydrate is global: established API manufacturers and exporters are located in India and China (major active pharmaceutical ingredient hubs), with historical and contemporary manufacturing reported in parts of Europe, North America, and other regions. Online supplier directories and pharma industry listings show multiple manufacturers and exporters in India and China as primary sources for commercial ampicillin trihydrate API.