Azithromycin dihydrate price December 2025 and outlook (see chart below)

  • India:US$137.94/KG, -3.7% down
The chart below summarizes Azithromycin dihydrate price trend per region, as well as the outlook. It takes a moment to load.

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Azithromycin dihydrate price index

This post is a summary of the Azithromycin dihydrate price developments. The price developments of Azithromycin dihydrate are expressed in US$ prices converted FX rates applicable at the time when the price was valid. Azithromycin dihydrate price index developments are calculated from multiple separate sources of data to ensure statistical accuracy.

The outlook for Azithromycin dihydrate prices is generated from different inputs including:

  • Very recent price developments of immediate cost drivers of Azithromycin dihydrate prices
  • Recent price developments of underlying feedstocks which drive the price of Azithromycin dihydrate
  • Market futures for both cost drives and feedstocks of Azithromycin dihydrate prices
  • Adjustment of current supply/demand imbalances in the Azithromycin dihydrate market
  • Longer term trends in likely demand conditions

What is Azithromycin dihydrate and what is it used for

Azithromycin dihydrate is the dihydrate crystalline form of azithromycin, an azalide (macrolide-type) antibiotic derived from erythromycin. It is an orally bioavailable antibacterial agent that inhibits bacterial protein synthesis and is used to treat a variety of mild-to-moderate bacterial infections (for example respiratory tract infections, skin and soft-tissue infections, and certain sexually transmitted infections) where the causative organisms are susceptible to azithromycin.

How is Azithromycin dihydrate produced

Azithromycin dihydrate is typically prepared by converting azithromycin (or its monohydrate) into the dihydrate by controlled crystallization. Published processes include dissolving azithromycin in an organic–aqueous solvent system (commonly acetone–water or similar mixtures), adjusting pH and temperature, and adding a base or incremental water to induce formation of the dihydrate crystals, followed by isolation and drying. Several patent filings and industrial process descriptions give stepwise crystallization procedures to obtain a stable dihydrate form with low impurity levels.

How large is the global market for Azithromycin dihydrate

Market-research reports that separate the azithromycin API/formulation market estimate the broader azithromycin market in the multi-billion USD range (market estimates around USD ~7–7.8 billion for azithromycin overall in the early-to-mid 2020s, with projected growth through the 2020s). Specialist reports focused on azithromycin dihydrate as an API put the dihydrate-specific market in the lower-single-digit-billion to sub-billion range (sample published estimates for the azithromycin dihydrate market center around roughly USD 1.2 billion in 2024 with multi-year forecasts showing mid single-digit CAGRs). Note that reported values differ by source and by whether they cover the API alone, finished dosage forms, or the whole azithromycin product family—so figures should be interpreted according to each report’s scope.

Where is Azithromycin dihydrate produced

Azithromycin dihydrate (API) is manufactured in multiple regions worldwide. Large volumes of azithromycin APIs and finished azithromycin products are produced in India and China (major generic API and finished-dose manufacturing hubs), with additional production by multinational pharmaceutical companies in Europe and other regions. Directory and supplier listings show numerous API manufacturers and exporters (Indian API houses, specialized contract manufacturers and several Chinese and international producers) supplying azithromycin dihydrate for use in tablet and suspension production. Manufacturing is therefore geographically distributed, with India particularly prominent among generic API suppliers.

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