Clopidogrel Bisulphate price December 2025 and outlook (see chart below)
- India:US$43.73/KG, -0.5% down
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Clopidogrel Bisulphate price index
This post is a summary of the Clopidogrel Bisulphate price developments. The price developments of Clopidogrel Bisulphate are expressed in US$ prices converted FX rates applicable at the time when the price was valid. Clopidogrel Bisulphate price index developments are calculated from multiple separate sources of data to ensure statistical accuracy.
The outlook for Clopidogrel Bisulphate prices is generated from different inputs including:
- Very recent price developments of immediate cost drivers of Clopidogrel Bisulphate prices
- Recent price developments of underlying feedstocks which drive the price of Clopidogrel Bisulphate
- Market futures for both cost drives and feedstocks of Clopidogrel Bisulphate prices
- Adjustment of current supply/demand imbalances in the Clopidogrel Bisulphate market
- Longer term trends in likely demand conditions
What is Clopidogrel Bisulphate and what is it used for
Clopidogrel bisulphate is the sulfate (bisulfate) salt form of clopidogrel, an oral thienopyridine antiplatelet agent that irreversibly inhibits the P2Y12 receptor on platelets. It is used to reduce the risk of arterial blood clots and is commonly prescribed to prevent heart attacks, strokes, and complications after placement of coronary stents — often given alone or together with aspirin as dual antiplatelet therapy.
How is Clopidogrel Bisulphate produced
Production generally starts from the clopidogrel free base which is synthesized via multi-step organic chemistry routes; the free base is then converted into the bisulfate salt by treatment with sulfuric (or related) acid in organic solvents and isolated as a crystalline form (various patented processes describe solvent choice, temperature control and crystallization of specific polymorphs). Large-scale methods and industrial preparations emphasize GMP controls, solvent recovery and salt-form crystallization to give a stable API suitable for formulation.
How large is the global market for Clopidogrel Bisulphate
Market estimates vary by source and scope (API vs finished-dose products). Recent industry reports place the clopidogrel market in the multi-billion USD range — for example, one market analysis projected around $11.9 billion in 2024 with continued growth into 2025, while a specialized clopidogrel-bisulfate report estimated roughly $1.5 billion for 2023 (differences reflect whether they measure API shipments, finished drug sales, regional coverage and report methodology). In short: reported figures vary, but multiple market research providers show a substantial, growing global market measured in the low-to-double digit billions (USD) depending on the scope.
Where is Clopidogrel Bisulphate produced
Originator/plasma-brand supply historically came from major pharma companies (e.g., the Plavix originator partnership), but today the bulk of API production and generic manufacture is concentrated in established pharmaceutical chemical clusters — notably manufacturers in India and China, with additional suppliers in Europe, North America and other regions. Directories of API suppliers list many Indian and Chinese producers as primary exporters of clopidogrel API and bisulfate salt.
