Hydrochlorothiazide price December 2025 and outlook (see chart below)
- India:US$23.64/KG, -0.2% down
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Hydrochlorothiazide price index
This post is a summary of the Hydrochlorothiazide price developments. The price developments of Hydrochlorothiazide are expressed in US$ prices converted FX rates applicable at the time when the price was valid. Hydrochlorothiazide price index developments are calculated from multiple separate sources of data to ensure statistical accuracy.
The outlook for Hydrochlorothiazide prices is generated from different inputs including:
- Very recent price developments of immediate cost drivers of Hydrochlorothiazide prices
- Recent price developments of underlying feedstocks which drive the price of Hydrochlorothiazide
- Market futures for both cost drives and feedstocks of Hydrochlorothiazide prices
- Adjustment of current supply/demand imbalances in the Hydrochlorothiazide market
- Longer term trends in likely demand conditions
What is Hydrochlorothiazide and what is it used for
Hydrochlorothiazide is a thiazide-type diuretic (“water pill”) that works by reducing sodium and water re-absorption in the distal convoluted tubule of the kidneys, thereby increasing urine output and lowering blood pressure. It is used primarily to treat hypertension (high blood pressure) and to reduce oedema (fluid retention) caused by heart failure, liver disease (cirrhosis), kidney disease, or medications such as estrogens or corticosteroids.
How is Hydrochlorothiazide used
Hydrochlorothiazide is administered orally (tablets or capsules) under prescription, and its dosage depends on the indication (hypertension vs fluid retention), the patient’s kidney and liver status, and other medications. It is often used alone, but can also be combined with other antihypertensive agents (for example ACE inhibitors, ARBs) when monotherapy is insufficient. Because it increases urine output, monitoring of electrolytes (especially potassium, magnesium), renal function and volume status is required. Note: This information is for overview only and not a substitute for professional medical advice.
How large is the global market for Hydrochlorothiazide and where is it produced
Regarding market size: some sources estimate the global thiazide diuretics market (of which hydrochlorothiazide is the dominant segment) at around USD 104 million in 2023, with growth expected to ~USD 210 million by 2033. More specific combination-drug markets (e.g., hydrochlorothiazide + candesartan) are valued at several billions; for instance, the global candesartan + hydrochlorothiazide market was projected at USD 5.729 billion in 2025 and USD 10.847 billion by 2033.
Production & manufacturing: Hydrochlorothiazide active pharmaceutical ingredient (API) is manufactured in multiple countries. For example, one Indian manufacturer (IPCA Laboratories Ltd, Ratlam, Madhya Pradesh) produces the API under GMP. Other API manufacturers and suppliers are located in India, China, Poland and the Czech Republic among others. Late-stage formulation manufacturing (tablets) is done by many generic drug companies globally.
In summary: Hydrochlorothiazide is a widely used diuretic and antihypertensive agent; it is delivered orally; its market is sizeable especially in combinations and is expanding; and its manufacture is global with strong footprint in India, China and Europe.