Hydroxychloroquine sulphate price December 2025 and outlook (see chart below)
- India:US$103.15/KG, -0.1% down
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Hydroxychloroquine sulphate price index
This post is a summary of the Hydroxychloroquine sulphate price developments. The price developments of Hydroxychloroquine sulphate are expressed in US$ prices converted FX rates applicable at the time when the price was valid. Hydroxychloroquine sulphate price index developments are calculated from multiple separate sources of data to ensure statistical accuracy.
The outlook for Hydroxychloroquine sulphate prices is generated from different inputs including:
- Very recent price developments of immediate cost drivers of Hydroxychloroquine sulphate prices
- Recent price developments of underlying feedstocks which drive the price of Hydroxychloroquine sulphate
- Market futures for both cost drives and feedstocks of Hydroxychloroquine sulphate prices
- Adjustment of current supply/demand imbalances in the Hydroxychloroquine sulphate market
- Longer term trends in likely demand conditions
What is Hydroxychloroquine sulphate and what is it used for
Hydroxychloroquine sulfate is the sulphate salt form of the drug Hydroxychloroquine (HCQ). In medicine it is used for the prevention and treatment of malaria in regions where sensitive strains exist, and also for chronic autoimmune/inflammatory disorders such as Systemic Lupus Erythematosus (SLE) and Rheumatoid Arthritis (RA). It was also extensively discussed (though not proven) for treatment or prophylaxis of COVID‑19 during the pandemic. Its mode of action includes immunomodulatory and anti‑inflammatory effects in the autoimmune uses, and antimalarial activity via interference with parasite activity and host cell processes.
Despite its uses, it carries risks and side‑effects (e.g., effects on heart rhythm, retina) and therefore its use must follow approved indications.
How is Hydroxychloroquine sulphate produced
The production of hydroxychloroquine sulphate involves a multi‑step chemical synthesis of the active molecule hydroxychloroquine followed by conversion to the sulphate salt form. One documented patent method begins with the condensation of 4,7‑dichloroquinoline with an appropriate amine side‑chain under catalyst conditions, producing hydroxychloroquine, which is then reacted with sulphuric acid to yield hydroxychloroquine sulphate.
On the manufacturing side, discussions around continuous manufacture and scale‑up have noted that emerging manufacturing hubs (for example in India, China and other Asian countries) are increasingly used to meet global demand.
In terms of industrial capacity, it’s noted (pre‑pandemic) that in India the production capacity for hydroxychloroquine was around 480 tons annually.
How large is the global market for Hydroxychloroquine sulphate and where is it produced
Market estimates vary somewhat depending on scope (salt form, tablets, formulation). For example, one report values the hydroxychloroquine market at about USD 1.27 billion in 2022 and projects USD 3.25 billion by 2030 (CAGR ~12.4 %). Another source puts the hydroxychloroquine salt (tablets) market at USD 1.8 billion in 2024 and projected to reach USD 2.6 billion by 2032 (CAGR ~5.2 %). Yet another reported that the hydroxychloroquine market was USD 2.8 billion in 2025 and projected to USD 5.1 billion by 2033 (CAGR ~7.7 %). p>On the production side, it is reported that India accounts for around 70 % of global hydroxychloroquine output. Raw‑material APIs are often procured from China.
Thus the key production geographies include India (major manufacturer of final drug), China (key supplier of raw materials/intermediates) and other pharmaceutical manufacturing hubs in Asia and globally.
